Publications

David J Wooten, Réka Albert (2020). synergy - A Python library for calculating, analyzing, and visualizing drug combination synergy. Bioinformatics.

Christian T Meyer, David J Wooten, Carlos F Lopez, Vito Quaranta (2020). Charting the Fragmented Landscape of Drug Synergy. Trends in Pharmacological Sciences.

PDF Project DOI

David J Wooten*, Sarah M Groves*, Darren R Tyson, Qi Liu, Jing S Lim, Réka Albert, Carlos F Lopez, Julien Sage, Vito Quaranta (2019). Systems-level network modeling of Small Cell Lung Cancer subtypes identifies master regulators and destabilizers. PLoS Comput Biol.

PDF Project Project DOI

Akshitkumar M Mistry, David J Wooten, L Taylor Davis, Bret C Mobley, Vito Quaranta, Rebecca A Ihrie (2019). Ventricular-Subventricular Zone Contact by Glioblastoma is Not Associated with Molecular Signatures in Bulk Tumor Data. Scientific Reports.

Christian T Meyer*, David J Wooten*, B Bishal Paudel*, Joshua Bauer, Keisha N Hardeman, David Westover, Christine M Lovly, Leonard A Harris, Darren R Tyson, Vito Quaranta (2019). Quantifying Drug Combination Synergy along Potency and Efficacy Axes. Cell Systems.

PDF Project DOI

David J Wooten*, Christian T Meyer*, Vito Quaranta, Carlos F Lopez (2019). A Consensus Framework Unifies Multi-Drug Synergy Metrics. bioRxiv.

PDF Project DOI

Akshata R Udyavar*, David J Wooten*, Megan Hoeksema, Mukesh Bansal, Andrea Califano, Lourdes Estrada, Santiago Schnell, Jonathan M Irish, Pierre P Massion*, Vito Quaranta* (2017). Novel hybrid phenotype revealed in small cell lung cancer by a transcription factor network model that can explain tumor heterogeneity. Cancer Research.

PDF Project DOI

David J Wooten, Vito Quaranta (2017). Mathematical models of cell phenotype regulation and reprogramming: Make cancer cells sensitive again!. Biochimica et Biophysica Acta - Reviews on Cancer.